工作、学习经历

2021.04 ~ 至今，浙江大学，助理研究员

2014.09 ~ 2021.03，浙江大学药物信息学研究所，药物分析学，博士研究生

2010.09 ~ 2014.06，浙江大学药学院，药学，本科

社会兼职

浙江省生物信息学会智能药学委员会委员

获奖情况

ESI高被引论文，高被引论文受到引用的次数已将其归入Biology & Biochemistry 学术领域同一出版年最优秀的前 1% 之列

2018年江苏省研究生“现代中医中药创新与传承”学术创新论坛一等奖

2017年上海市“中医药系统生物学”研究生学术论坛二等奖

主持或参与科研项目情况

2021E10014，阿尔茨海默症模型小鼠海马组织三维空间转录组图谱构建，浙江省神经药理学与转化研究重点实验室开放基金，2022-01-01至2023-12-31，主持

81973701，基于小鼠大脑空间单细胞图谱的三七-人参抗脑缺血再灌注损伤作用比较研究，国家自然科学基金面上项目，2020-01-01至2023-12-31，参与

81774153，基于动态“失和/求和”网络的参麦方组分配伍优化研究，国家自然科学基金面上项目，2018-01-01至2021-12-31，参与

LZ20H290002，基于单细胞空间转录组测序SPATIAL-seq的参麦方治疗冠心病气虚血瘀证网络调控机制研究，浙江省基金重点项目，2020-01-01至2023-12-31，参与

发表论文

1.  Liao J, Lu X, Shao X, Zhu L, Fan X. Uncovering an Organ's Molecular Architecture at Single-Cell Resolution by Spatially Resolved Transcriptomics. Trends Biotechnol (IF 19.531). 2021 Jan;39(1):43-58.

2.  Shao X, Liao J (Co-First), Li C, Lu X, Cheng J, Fan X. CellTalkDB: a manually curated database of ligand-receptor interactions in humans and mice. Brief Bioinform (IF 11.622). 2021 Jul 20;22(4):bbaa269.

3.  Liao J, Hao C, Huang W, Shao X, Song Y, Liu L, Ai N, Fan X. Network pharmacology study reveals energy metabolism and apoptosis pathways-mediated cardioprotective effects of Shenqi Fuzheng. J Ethnopharmacol (IF 4.364). 2018 Dec 5;227:155-165.

4.  Shao L, Liao J (Co-First), Qian J, Chen W, Fan X. MetaGeneBank: a standardized database to study deep sequenced metagenomic data from human fecal specimen. BMC Microbiol (IF 3.601). 2021 Sep 30;21(1):263.

5.  Cheng J, Liao J, Shao X, Lu X, Fan X. Multiplexing Methods for Simultaneous Large-Scale Transcriptomic Profiling of Samples at Single-Cell Resolution. Adv Sci (IF 16.8). 2021 Sep;8(17):e2101229.

6.  Shao X, Yang H, Zhuang X, Liao J, Yang P, Cheng J, Lu X, Chen H, Fan X. scDeepSort: a pre-trained cell-type annotation method for single-cell transcriptomics using deep learning with a weighted graph neural network. Nucleic Acids Res (IF 16.973). 2021 Sep 9:gkab775.

7.  Shao X, Lu X, Liao J, Chen H, Fan X. New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data. Protein Cell (IF 14.870). 2020 Dec;11(12):866-880.

8.  Shao X, Liao J, Lu X, Xue R, Ai N, Fan X. scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data. iScience (IF 5.458). 2020 Mar 27;23(3):100882.

9.  Xue R, Liao J, Shao X, Han K, Long J, Shao L, Ai N, Fan X. Prediction of Adverse Drug Reactions by Combining Biomedical Tripartite Network and Graph Representation Model. Chem Res Toxicol (IF 3.734). 2020 Jan 21;33(1):202-210.

10.  Shao L, Xue R, Lu X, Liao J, Shao X, Fan X. Identify differential genes and cell subclusters from time-series scRNA-seq data using scTITANS. Comput Struct Biotechnol J (IF 7.272). 2021 Jul 26;19:4132-4141.

11.  Shao X, Wang Y, Lu X, Hu Y, Liao J, Li J, Chen X, Yu Y, Ai N, Ying M, Fan X. A Clinical Genomics-Guided Prioritizing Strategy Enables Selecting Proper Cancer Cell Lines for Biomedical Research. iScience (IF 5.458). 2020 Oct 28;23(11):101748.

12.  Shao X, Lv N, Liao J, Long J, Xue R, Ai N, Xu D, Fan X. Copy number variation is highly correlated with differential gene expression: a pan-cancer study. BMC Med Genet (IF 2.104). 2019 Nov 9;20(1):175.

13.  Li Z, Zhang X, Liao J, Fan X, Cheng Y. An ultra-robust fingerprinting method for quality assessment of traditional Chinese medicine using multiple reaction monitoring mass spectrometry. J Pharm Anal (IF 4.76). 2021 Feb;11(1):88-95.

14.  Li Z, Liu T, Liao J, Ai N, Fan X, Cheng Y. Deciphering chemical interactions between Glycyrrhizae Radix and Coptidis Rhizoma by liquid chromatography with transformed multiple reaction monitoring mass spectrometry. J Sep Sci (IF 3.643). 2017 Mar;40(6):1254-1265.

15.  Chen Q, Ai N, Liao J, Shao X, Liu Y, Fan X. Revealing topics and their evolution in biomedical literature using Bio-DTM: a case study of ginseng. Chin Med (IF 5.452). 2017 Sep 12;12:27.

16.  Liu Y, Ai N, Liao J, Fan X. Transcriptomics: a sword to cut the Gordian knot of traditional Chinese medicine. Biomark Med (IF 2.854). 2015;9(11):1201-13.